Christopher
Q. Lan, Ph.D.
Associate Professor
Tel: (613) 562-5800 ext. 2050
Fax: (613) 562-5172
E-mail: Christopher.Lan@uottawa.ca
Current
Research Interests
1. Biotechnology
and Bioprocesses
a.
Microalgal Biotechnology
b.
Biofuels
c.
Novel Alternatives to
Antibiotics
d.
Recombinant protein
expression
e.
Fermentation process
development, modeling and optimization
f.
Protein purification
2. Membrane Technologies
a.
Membrane Separation
b.
Membrane Cooling
Selected Publications
Book and book
chapters
Lan CQ and Wang B, Microalgae
for Biofuel production and CO2
Sequestration, Nova Science Publishers, Hauppauge, NY, ISBN: 978-1-61668-151-7 (2010)
Lan CQ and Wang B, Biofixation of CO2 by micro-organisms, in Developments and innovation in carbon
capture and storage (CCS) technology, Woodhead
Energy Series No. 8, M. Mercedes
Maroto-Valer Ed., Woodhead Publishing, Cambridge, UK, ISBN-13: 978 1 84569 533 0 (2010)
Wang B, Dorval-Courchesne NM, Mu Y, Lan CQ, Bio-mitigation and biofuel production using microalgae, in
Marine Phytoplankton William T. Kersey and Samuel P. Munger,
Ed., Nova Science Publishers, Inc. Hauppauge , NY , USA, at prepress 978-1-60741-087-4 (2010)
Peer-reviewed
articles
Wang B. and Lan CQ, Removal of nitrate,
ammonium and phosphate from artificial or secondary municipal wastewater by the
green alga Neochloris oleoabundans, Bioresource Technology, accepted, 2011
Wang B. and Lan CQ, Optimizing the lipid
production of the green alga Neochloris oleoabundans using
Box-Behnken experimental design, Canadian Journal of
Chemical Engineering, accepted, 2011
Potvin G., Debska D., Lan CQ, Zhang Z., Effects of operating
conditions on the photobioreactor cultivation of Chlorella
vulgaris, Biomass and Bioenergy, accepted, 2011
Schissler TA, Stapleton J, Binder K, Lan CQ, Hardcastle S and Kenny GP, Ice-cooling vest on tolerance for exercise under uncompensable heat stress, Journal of Occupational and Environmental Hygiene, accepted (2011)
Mahmoodi,
N.M., Hayati, B., Arami, M.,
Lan, C. Adsorption of textile dyes on Pine Cone from colored wastewater: Kinetic, equilibrium and thermodynamic
studies, Desalination 268: 117-125, 2011
Debska D., Potvin G., Lan C, Zhang Z., Effects of medium composition
on the growth of Chlorella vulgaris during photobioreactor
batch cultivations, Journal of Biobased Materials and
Bioenergy, 4: 68-72, 2010
Dorval-Courchesne NM, Parisien
A, Wang B. and Lan CQ, Enhancement
of lipid production using biochemical, genetic and transcriptional
factor engineering approaches: the promises and challenges, J Biotechnol. IF:
2.565 141: 31-41 (2009)
Wang Z. and Lan C.Q., Excess molar enthalpies of the
ternary mixtures:
methyl tert-butyl ether (or di-isopropyl ether) + n-octane +2-methylpentane at 293.15 K, Can J. Chem. Eng., 87: 598-604 IF: 0.463 (2009)
Parisien
A, Lan CQ, Classification of bacterial cell wall hydrolysases
and their potentials as novel alternatives to antibiotics - a response to the letter of Biziulevicius
and Kazlauskaite, J. Appl. Microbiol.,
106: 1754-1759, IF: 2.501 (2009)
Dorval Courchesne N.M., Parisien A., Wang B. and Lan C.Q., Production and applications of phage and phage-encoded lytic enzymes, Recent Pat Biotechnol. 3:37-45 (2009)
Li Y., Horsman M., Wang B., Wu N., and Lan
C.Q., Effects of nitrogen sources on cell growth and lipid production of Neochloris
oleoabundans, Appl Microbiol
Biotechnol, 81 (4), pp. 629-636 (2008)
Razvi A., Zhang Z, and Lan C.Q., Effects of Glucose and Nitrogen Source Concentration on
Batch Fermentation Kinetics of Lactococcus lactis under Hemin-Stimulated
Respirative Condition, Biotechnol
Prog, 24: 852-858 (2008)
Li Y., Horsman M, Wu N, and Lan C.Q., Dubois-Calero N., Biofuels
from Microalgae, Biotech Prog, 24: 815-820 (2008)
Wang B., Li Y., Wu N., and Lan C.Q., CO2
Bio-Mitigation Using Microalgae, App Microbiol Biotech, 79: 707-718
(2008)
Zhang J. and Lan CQ, Laser-generated Ni and Co Nanoparticles in
Organic Media, Mat. Letts. 62:
1521-1524 (2008)
Parisien A; Allain B; Zhang J; Mandeville R; and Lan C.Q., Novel Alternatives to Antibiotics: Bacteriophages, Bacterial Cell Wall Hydrolases, and Antimicrobial Peptides, J Appl Microbiol, 104: 1-13 (2008)
Oddone G, Lan CQ, Rawsthorne H, Mills DA, and Block DE, Optimization of Fed Batch Production of the Model Recombinant Protein GFP in Lactococcus lactis, Biotechnol Bioeng Volume 96: 1127-1138 (2007).
Lan CQ, Oddone G, Mills DA, and Block DE, Kinetics of Lactococcus lactis Growth and Metabolite Formation under Aerobic or Anaerobic Conditions at the Presence or Absence of Hemin, Biotechnol Bioeng, 95(6): 1070 ¨C 1080 (2006)
Zhang J, Lan CQ, Post M, Simard B, Deslandes Y, and Hsieh TH, Design of nanoparticles as drug carriers for cancer therapy. Cancer, Genomics & Proteomics 3: 147-157 (2006)
Lan CQ, Kodama D, Wang Z and Lu BC-Y, Excess molar enthalpies of the ternary mixtures (1-hexene + tetrahydrofuran or 2-methyltetrahydrofuran + methyl tert-butyl ether) at the temperature 298.15 K. J Chem Thermodynamics, 38: 1606-1611 (2006)
Wang Z, CQ Lan, BC-Y Lu, Excess molar
enthalpies of the ternary mixtures:
Lan Q, A Bassi, J-X Zhu and A Margaritis, Continuous Protein Recovery with a Liquid-Solid Circulating Fluidized-Bed Ion Exchanger. AIChE J. 48(2) 252-261, 2002
Lan Q, A Bassi, J-X Zhu and A Margaritis, Continuous Protein Recovery from Whey Using Liquid Solid Circulating Fluidized Bed Ion Exchange Extraction. Biotechnol Bioeng. 78(2) 157-163, 2002
Lan Q, A Bassi, J-X Zhu and A Margaritis, A Modified Langmuir Model for the Prediction of the Effects of Ionic Strength on the Equilibrium Characteristics of Protein Adsorption onto Ion Exchange/Affinity Adsorbents. Chem Eng J 179-186 (2001)
Lan Q, J-X Zhu, A Bassi, A Margaritis, Y Zheng and G Rowe, Continuous Protein Recovery Using a Liquid-Solid Circulation Fluidized Bed Ion Exchange System: Modelling and Experimental Studies. Can J Chem Eng 78: 858-866 (2000)
Rowe GE, A Margaritis, Q Lan, AS Bassi and J-X Zhu, A new kinetic model of protein adsorption on suspended anion-exchange resin particles, Biotechnol Bioeng, 65(6) 613-621, 1999
Patents
Bassi A. S., J. Zhu, Q. Lan, A.
Margaritis, Y. Zheng, Continuos ion exchange using liquid-solids circulating
fluidized bed, CA2322348, (2008)
Bassi A. S., J. Zhu, Q. Lan, A.
Margaritis, Y. Zheng, Methods for recovering ionic products, USA Patent
6,887,386, B2 (2005)
Bassi A. S., J. Zhu, Q. Lan, A.
Margaritis, Y. Zheng, Liquid-solids circulating fluidized bed, USA Patent
6,716,344, (2004)
Conference
Presentations
Dorval Courchesne N. M., Parisien A.,
Lan C. Q., Enhancement of lipid production using metabolic approaches (poster),
58th CSChE,
Wu N., Li Y., Wang B., Lan C.Q.£¬Photoatutotrophic
and Mixotrophic Cultivation of Green Alga Neochloris
oleoabundans Using Various Carbon Sources£¬58th
CSChE, Ottawa, Oct 2008, Ottawa, ON, Canada
Debska D., Lan C., Zhang J£¬High Density Cultivation of Chlorella
vulgaris for Use as a Feed in Biodiesel Production£¬58th CSChE,
Wang B., Lan C.
Q., Optimization of Medium for Lipid Production by Green Alga Neochloris oleoabundans£¬58th CSChE,
Parisien A.,
Dorval Courchesne N.M., Hussack G., Lan C.Q. , Tanha J, Over-expression
of Single Domain Antibody Against Clostridium difficile
toxin A in Escherichia coli, 58th CSChE,
Ottawa, Oct 2008, Ottawa, ON, Canada
Shemshaki F, Lan C.Q., Tremblay A.Y., Heat Transfer in
Vacuum Membrane Distillation, 58th
CSChE,
Thian¨¦ Diagne B., Seung C., Lan C.Q., Membrane Facilitated
Evaporative Cooling£¬58th CSChE,
Parisien A., Hussack G., and Lan, C. Q., Over-expression of single domain antibody in Escherichia
coli, Gui-E Cheng, Christopher Q.
Lan, Biomass separation using microfiltration membranes, 10th
Ontario-Quebec Biotechnology conference, Jul 2008, Sherbrooke,
Quebec, Canada
Gui-E Cheng, Christopher Q.
Lan, Biomass separation using microfiltration membranes, 10th
Ontario-Quebec Biotechnology conference, Jul 2008, Sherbrooke,
Quebec, Canada
Nan Wu, Yanqun Lia, Bei Wang, Christopher Q. Lan, Mixotrophic
cultivation of green alga Neochloris oeloabundans,
10th Ontario-Quebec Biotechnology conference, Jul 2008, Sherbrooke, Quebec, Canada
Yanqun Li, Mark Horsman, Nan Wu, Christopher Q. Lan,
Biofuels from Microalgae, 57th CSChE Conference,
Albert Parisien and Christopher Q. Lan, Food-Grade
Biotechnology, an Innovation Concept for Novel Food and Drug Production, 57th CSChE Conference, Edmonton, AB, Canada, Oct 2007
Yanqun Li, Nan Wu, Mark Horsman, Christopher Q. Lan,
On-Site CO2 Fixation Using an Alternate Photoautotrophic and Heterotrophic
Cultivation of Microalgae, Workshop on in-situ CO2 Removal ISCR 2007, Ottawa,
Canada
Mark Horsman, Yanqun Li, Nan Wu, Nathalie
Dubois-Calero, Christopher Q. Lan, Alternate Photoautotrophic and Heterotrophic
Cultivation of Microalgae¡±, the 9th Annual
Azher Razvi,
Albert Parisien, Azher Razvi, and Christopher Q.
Lan, ¡°Effect of Medium Composition on the Cell Growth of Lactic Acid Bacteria
and the Propagation of LAB Bacteriophages¡±, the 9th Annual
Azher Razvi, Julia Stawski,
Bo Yu, Christopher Q. Lan, ¡°Sulfate
Removal from High Concentrate Sodium Chloride Brines from Chloralkali
Industry with NF Membrane¡±, North American Membrane Society Conference (
Edward Thompson, Qingdao (Chris) Lan, Peter Dalal,
Mattew Price, ¡°Xanthan Production from Wheat Starch¡±,
Sixth International Hydrocolloids Conference, July 2002, Guelph, Ontario,
Canada
Lan Q., A.S. Bassi, J.-X. Zhu and A. Margaritis, ¡°An
Investigation on the Protein Adsorption in an LSCFB Ion Exchange System¡±,
Presentation at 49th Canadian Chemical Engineering Conference.
1999.10,
Lan, Q. and F. Chen, ¡°Effects of Nitrogen Sources on the
Cell Growth and Phycocyanin Biosynthesis of Spirulina platensis¡±.
Presentation at the 48th Canadian Chemical Engineering Conference.
Lan, Q., A. Bassi and A. Margaritis, J.-X. Zhu, and G. Rowe,
¡°Whey Protein Recovery in Liquid Solid
Circulating Fluidized Beds¡±. Presentation at 48th
Canadian Chemical Engineering Conference.
1998.10,