Text Box:  Christopher Q. Lan, Ph.D.

Assistant Professor

161 Louis Pasteur St., Room A408

Ottawa, Ontario, Canada, K1N 6N5

Tel: (613) 562-5800 ext. 2050

 Fax: (613) 562-5172

E-mail: Christopher.Lan@uottawa.ca

 

 

 

 

 

 

Research Interests

1. Bioprocesses

a.      Biofuels

b.      Novel Alternatives to Antibiotics

c.      Recombinant protein expression

d.      Fermentation process development, modelling and optimization

e.      Protein purification

2. Portable Microclimate Cooling Systems

3. Membrane Technologies

a.       Membrane Separation

b.      Membrane Cooling

4. Thermodynamics

 

 

Selected Peer-Reviewed Papers

 

Li Y., Horsman M, Wu N, Lan CQ, Dubois-Calero N., Biofuels from Microalgae, Biotech Prog. (2008)

Wang Z. and Lan C.Q., Excess molar enthalpies of the ternary mixtures: methyl tert-butyl ether (or di-isopropyl ether) + n-octane +2-methylpentane at 293.15 K, Can J. Chem. Eng. (2008)

Zhang J. and Lan CQ, Laser-generated Ni and Co Nanoparticles in Organic Media, Mat. Letts. 62: 1521-1524 (2008)

Parisien A; Allain B; Zhang J; Mandeville R; Lan, CQ, Novel Alternatives to Antibiotics: Bacteriophages, Bacterial Cell Wall Hydrolases, and Antimicrobial Peptides, J Appl Microbiol, 104: 1-13 (2008)

Oddone G, Lan CQ, Rawsthorne H, Mills DA, and Block DE,  Optimization of Fed Batch Production of the Model Recombinant Protein GFP in Lactococcus lactis, Biotechnol Bioeng Volume 96: 1127-1138 (2007).

Lan CQ, Oddone G, Mills DA, and Block DE, Kinetics of Lactococcus lactis Growth and Metabolite Formation under Aerobic or Anaerobic Conditions at the Presence or Absence of Hemin, Biotechnol Bioeng, 95(6): 1070 – 1080 (2006)

Zhang J, Lan CQ, Post M, Simard B, Deslandes Y, and Hsieh TH, Design of nanoparticles as drug carriers for cancer therapy. Cancer, Genomics & Proteomics 3: 147-157 (2006)

Lan CQ, Kodama D, Wang Z and Lu BC-Y, Excess molar enthalpies of the ternary mixtures (1-hexene  +  tetrahydrofuran or 2-methyltetrahydrofuran + methyl tert-butyl ether) at the temperature 298.15 K. J Chem Thermodynamics, Available online (2006)

Wang Z, CQ Lan, BC-Y Lu, “Excess molar enthalpies of the ternary mixtures: {tetrahydrofuran or 2-methyltetrahydrofuran + methyl tert-butyl ether + n-octane} at the temperature 298.15 K”, J Chem Thermodynamics, 38:572-577 (2006)

Wang Z, BC-Y. Lu, DY Peng, and CQ Lan, “Liebermann-Fried Model Parameters for Calculating Vapour-Liquid Equilibria of Oxygenate and Hydrocarbon Mixtures”, Journal of Chinese Institute of Engineers, 28(7): 1-17, 2005

Lan Q, A Bassi, J-X Zhu and A Margaritis, “Continuous Protein Recovery with a Liquid¯Solid Circulating Fluidized-Bed Ion Exchanger”. AIChE J. 48(2) 252-261, 2002

Lan Q, A Bassi, J-X Zhu and A Margaritis “Continuous Protein Recovery from Whey Using  Liquid Solid Circulating Fluidized Bed Ion Exchange Extraction”. Biotechnol Bioeng. 78(2) 157-163, 2002

Lan Q, A Bassi, J-X Zhu and A Margaritis, “A Modified Langmuir Model for the Prediction of the Effects of Ionic Strength on the Equilibrium Characteristics of Protein Adsorption onto Ion Exchange/Affinity Adsorbents”. Chem Eng J 179-186 (2001)

Lan Q, J-X Zhu, A Bassi, A Margaritis, Y Zheng and G Rowe, “Continuous Protein Recovery Using a Liquid-Solid Circulation Fluidized Bed Ion Exchange System: Modelling and Experimental Studies.” Can J Chem Eng 78: 858-866 (2000)

Rowe GE, A Margaritis, Q Lan, AS Bassi and J-X Zhu, “A new kinetic model of protein adsorption on suspended anion-exchange resin particles”, Biotechnol Bioeng, 65(6) 613-621, 1999

 

Patents

 

Bassi A. S., J. Zhu, Q. Lan, A. Margaritis, Y. Zheng, 2005 “Methods for recovering ionic products” USA Patent 6,887,386, B2  2005

A. S. Bassi, J. Zhu, Q. Lan, A. Margaritis, Y. Zheng, 2004 “Liquid-solids circulating fluidized bed” USA Patent 6,716,344, 2004

 

Conference Abstracts and Technical Reports

 

Yanqun Li, Nan Wu, Mark Horsman, Christopher Q. Lan, On-Site CO2 Fixation Using an Alternate Photoautotrophic and Heterotrophic Cultivation of Microalgae, Workshop on in-situ CO2 Removal ISCR 2007, Ottawa, Canada

Mark Horsman, Yanqun Li, Nan Wu, Nathalie Dubois-Calero, Christopher Q. Lan, « Alternate Photoautotrophic and Heterotrophic Cultivation of Microalgae”, the 9th Annual Ontario Quebec CSChE Biotechnology Meeting, Toronto, June 2007

Azher Razvi, Jason Zhang, Christopher Q. Lan , “Energy Sufficiency and Energy Limited growth of Lactococcus lactis under Hemin-Stimulated Respirative Conditions”, the 9th Annual Ontario Quebec CSChE Biotechnology Meeting, Toronto, June 2007

Albert Parisien, Azher Razvi, and Christopher Q. Lan, “Effect of Medium Composition on the Cell Growth of Lactic Acid Bacteria and the Propagation of LAB Bacteriophages”, the 9th Annual Ontario Quebec CSChE Biotechnology Meeting, Toronto, June 2007

Azher Razvi, Julia Stawski, Jason Z. Zhang, and Christopher Q. Lan, “A Study of Hemin-Stimulated Respiration Kinetics and Product Formation of Lactococcus lactis in Chemostat”, 8th CsChE Ontario-Quebec Biotechnology Meeting, Montreal, Quebec, Canada, May 25th, 2006

Bo Yu, Christopher Lan, “Sulfate Removal from High Concentrate Sodium Chloride Brines from Chloralkali Industry with NF Membrane”, North American Membrane Society Conference (NAMS), June, 2005, Providence, Rhode Island, USA

Edward J. Thompson, Chris Q. Lan, Matthew Price, and Tim Woods, “Milestone Report: Carbohydrate Specification, Medium Optimization and Pilot Design for the Development of a Commercial Xanthan Fermentation Process”, Rebus Corporation, April, 2002

Edward Thompson, Qingdao (Chris) Lan, Peter Dalal, Mattew Price, “Xanthan Production from Wheat Starch”, Sixth International Hydrocolloids Conference, July 2002, Guelph, Ontario, Canada

Edward J. Thompson, Chris Q. Lan, Peter Dalal, and Matthew Price, “Research & Development Report I: Culture Development & Xanthan Fermentation Using Xanthomonas campestris R1”, Rebus Corporation, November, 2001

Lan Q., A.S. Bassi, J.-X. Zhu and A. Margaritis, “An Investigation on the Protein Adsorption in an LSCFB Ion Exchange System”, 49th Canadian Chemical Engineering Conference, October 1999, Saskatchewan, Ontario, Canada

Lan, Q. and F. Chen, “Effects of Nitrogen Sources on the Cell Growth and Phycocyanin Biosynthesis of Spirulina platensis”, the 48th Canadian Chemical Engineering Conference, London, Ontario, Canada, October 1998

Lan, Q., A. Bassi and A. Margaritis, J.-X. Zhu, and G. Rowe, “Whey Protein Recovery in Liquid Solid Circulating Fluidized Beds”, 48th Canadian Chemical Engineering Conference, October 1998, London, Ontario, Canada

 

Governmental Funding Sources

 

Canadian Foundation for Innovation (CFI)

Natural Science and Engineering Research Council of Canada (NSERC)

Canadian Institute of Health Research (CIHR)

Ontario Ministry of Research and Innovation

Ontario Centre of Excellence (OCE)

 

Undergraduate Courses

 

CHG 4381: Introduction to Biochemical Engineering

CHG 4360: Fermentation Technology

CHG 3326: Introduction to Phase Equilibria and Chemical Reaction Equilibria

CHG 3324: Fundamentals and Applications of Chemical Thermodynamics

 

Graduate Courses

 

CHG 8145: Selected Topics in Biotechnology

 

 

Reviewing Services for Academic Journals

 

Journal of membrane science

Biotechnology and Bioengineering

Microbial Cell Factories

Applied Microbiology and Biotechnology

Journal of Applied Polymer Science

Dairy Science and Technology